Curcumin For Inflammatory Bowel Disease? The herb turmeric has been utilized for a considerable length of time not only for its color, flavor and preservative quality, yet additionally, as a therapeutic cure.
Curcumin can treat a wide variety of inflammatory disorders; in fact, it is used as Ayurvedic medicine for many years.
In this article:
Inflammation and Disease
Anti-Inflammatory Agents
Curcumin’s Mitigating Properties
Obesity and Heart Disease
Inflammatory Bowel Diseases
Conclusion
Turmeric plant is found in India, some parts of Asia and also in Central America. South Asian people used turmeric as part of their Ayurvedic medicine for treating various illnesses like rheumatism, severe pain, fatigue, and breathing difficulties.
Currently, turmeric is recommended as a supplement for people suffering from:
Arthritis
Skin, stomach, gallbladder and liver problems
Inflammation
Cancer
Other conditions
Turmeric is used as powder, tablets, tea, extracts, and paste. Curcuminoids, the key active ingredient in turmeric, gives the yellow color. It is used as a coloring agent in food and in the cosmetics industry.
Some preliminary studies suggest that curcuminoids present in turmeric help in reducing the number of heart attacks in patients who underwent bypass surgery.
Curcuminoids can also be used to minimize skin irritation after radiation therapy for breast cancer. They can help in managing knee pain in osteoarthritis condition.
Curcumin or turmeric is a ginger family plant and is derived from the plant Curcuma longa, which is known for its therapeutic and culinary purposes. Turmeric contains three naturally-occurring phytochemicals called curcuminoids, which are curcumin, demethoxycurcumin, and bisdemethoxycurcumin; however the expressions “curcumin” and “curcuminoids” are the ones that are well-known. With its yellow trademark, curcumin is one of the important components of turmeric for 2-5%.
Researchers have found that curcumin has positive therapeutic effects to prevent and treat inflammation. Curcumin is non-toxic and has natural anti-inflammatory properties that are being studied nowadays in clinical trials.
Inflammation and Disease
Chronic inflammation brought about by long-term irritation, stress, infections, and injuries appeared to be healed by curcumin. However, when the acute reaction isn’t efficient, the body raises a chronic inflammatory reaction. Although intense inflammation has medicinal benefits, constant low-level inflammation sometimes predisposes to acute infections.
Inflammatory markers, lipid peroxides, and free radical levels can increase cell harm and can predispose to diseases. Recent studies have shown that chronic inflammation leads to numerous diseases, including diabetes, obesity, cardiovascular diseases, neurodegenerative diseases, inflammatory bowel diseases and particular types of cancers.
Cell signaling pathways are the body’s essential methods of communication, coordination, and management of every single cell action.
Anti-Inflammatory Agents
Anti-inflammatory and anti-tumor activities will decrease when medications like NSAIDs will be administered.
However, the reactions of long-term utilization of these medications, including upper gastrointestinal problems and cardiovascular illnesses, frequently exceed the benefits. Efforts are in progress to find safer NSAIDs that control inflammatory reactions while lessening symptoms related to long-term treatment.
Curcumin’s Mitigating Properties
Phenolic blends acquired from herbal sources, for instance, curcumin, have shown mitigating activities in vitro and in vivo. Infections and inflammation will recede by taking herbs and spices.
Broad clinical studies in recent decades have tended to curcumin’s pharmacokinetics, safety, and effectiveness against numerous illnesses. Curcumin has so many benefits in the body such as its anti-inflammatory properties, its cholesterol-lowering activities, and its antioxidant and antidiabetic effects.
Obesity and Heart Disease
Research done over the last two decades has demonstrated that being overweight is the main hazard for chronic illnesses, such as type 2 diabetes, atherosclerosis, and cancer. Obesity is a pro-inflammatory illness. People with type 2 diabetes also experience an increase in inflammation.
Adipose tissue is the main secretor of adipocytokines, where inflammation action starts. The atherosclerotic disease can develop through increased leptin levels and decreased levels of adiponectin.
Inflammatory Bowel Diseases
Two of the essential medicines for mild to moderate IBD are the anti-inflammatory drugs sulfasalazine and mesalamine, which work by repressing the COX and LOX pathways and the inflammatory processes. Unluckily, these drugs are with side effects, such as migraine, headache, nausea, loose bowels, and stomach pain.
In one study involving individuals with IBD, gastrointestinal symptoms were lessened with curcumin added to medicines. The researchers ended up finding that curcumin can help diminish the anti-inflammatory reactions of IBD. It was shown in the study that 4 out of 5 patients with ulcerative colitis and Crohn’s disease had improvement of symptoms after taking curcumin.
In fact, four of the five patients with ulcerative colitis did eliminate their prescribed drugs. These subjects detailed relief of their manifestations, including progressively shaped stools, less continuous defecations, and lessened stomach pain or cramping.
In Conclusion
Proof keeps on increasing in terms of curcumin’s role in controlling inflammatory response and in alleviating symptoms of inflammatory bowel diseases.
In the meantime, healthcare professionals suggest mixing curcumin with daily food servings to boost flavor and add color to food while also helping combat inflammation. More research should be done about the effectiveness of curcumin intake in the treatment of inflammatory disorders.
Recommended doses of turmeric are safe to take orally or topically. Higher dose or chronic usage of turmeric may result in gastrointestinal issues.
It is recommended to consult with your doctor before taking turmeric.
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